DISEASES

Disease-gene associations mined from literature

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Human genes for digenic disease

Digenic disease [DOID:0080578]

A polygenic disease that is characterized by expression of a phenotype that requires the presence of pathogenic variants in two different genes.

Synonyms:  digenic disease,  digenic disorder,  digenic syndrome,  digenic diseases,  DOID:0080578

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.