Human genes for rheumatic heart disease
Rheumatic heart disease [DOID:0050827]
A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.
Synonyms: rheumatic heart disease, DOID:0050827, rheumatic heart disorder, rheumatic heart syndrome, rheumatic heart diseases ...