DISEASES

Disease-gene associations mined from literature

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Human genes for Brooke-Spiegler syndrome

Brooke-Spiegler syndrome [DOID:0050693]

A skin disease that is characterized by the development of several types of tumors from the skin, has_material_basis_in heterozygous mutation in the CYLD gene on chromosome 16q12.

Synonyms:  Brooke-Spiegler syndrome,  BrookeSpiegler syndrome,  Brooke-Spiegler disease,  Brooke-Spiegler disorder,  Brooke-Spiegler syndromes ...

Linkouts:  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.