DISEASES

Disease-gene associations mined from literature

Human genes for diabetes insipidus

Diabetes insipidus [DOID:9409]

Diabetes insipidus (DI) is a condition characterized by excessive thirst and excretion of large amounts of severely diluted urine, with reduction of fluid intake having no effect on the concentration of the urine. There are several different types of DI, each with a different cause. The most common type in humans is central DI, caused by a deficiency of arginine vasopressin (AVP), also known as antidiuretic hormone (ADH). The second common type of DI is nephrogenic diabetes insipidus, which is caused by an insensitivity of the kidneys to ADH. It can also be an iatrogenic artifact of drug use.

Synonyms:  diabetes insipidus,  DOID:9409,  Diabetes insipidus (disorder),  Diabetes insipidus disorder,  Diabetes insipidus