DISEASES

Disease-gene associations mined from literature

Human genes for cleft lip

Cleft lip [DOID:9296]

Cleft lip (cheiloschisis) and cleft palate (palatoschisis), which can also occur together as cleft lip and palate, are variations of a type of clefting congenital deformity caused by abnormal facial development during gestation. A cleft is a fissure or opening—a gap. It is the non-fusion of the body's natural structures that form before birth. Approximately 1 in 700 children born have a cleft lip and/or a cleft palate. An older term is harelip, based on the similarity to the cleft in the lip of a hare.

Synonyms:  cleft lip,  DOID:9296,  Labium leporinum,  cheiloschisis,  cleft lip, unilateral, complete ...