DISEASES

Disease-gene associations mined from literature

Human genes for Hodgkin's lymphoma, nodular sclerosis

Hodgkin's lymphoma, nodular sclerosis [DOID:8838]

Hodgkin's lymphoma, previously known as Hodgkin's disease, is a type of lymphoma, which is a cancer originating from white blood cells called lymphocytes. It was named after Thomas Hodgkin, who first described abnormalities in the lymph system in 1832. Hodgkin's lymphoma is characterized by the orderly spread of disease from one lymph node group to another and by the development of systemic symptoms with advanced disease. When Hodgkins cells are examined microscopically, multinucleated Reed-Sternberg cells (RS cells) are the characteristic histopathologic finding. Hodgkin's lymphoma may be treated with radiation therapy, chemotherapy or hematopoietic stem cell transplantation, the choice of treatment depending on the age and sex of the patient and the stage, bulk and histological subtype of the disease.

Synonyms:  Hodgkin's lymphoma, nodular sclerosis,  DOID:8838,  Hodgkins lymphoma nodular sclerosis,  nodular sclerosis Hodgkin's lymphoma,  Classical Hodgkin lymphoma, nodular sclerosis ...