DISEASES

Disease-gene associations mined from literature

Human genes for muscular atrophy

Muscular atrophy [DOID:767]

Muscle atrophy, or disuse atrophy, is defined as a decrease in the mass of the muscle; it can be a partial or complete wasting away of muscle. When a muscle atrophies, this leads to muscle weakness, since the ability to exert force is related to mass. Muscle atrophy results from a co-morbidity of several common diseases, including cancer, AIDS, congestive heart failure, COPD (chronic obstructive pulmonary disease), renal failure, and severe burns; patients who have "cachexia" in these disease settings have a poor prognosis. Moreover, starvation eventually leads to muscle atrophy. Disuse of the muscles will also lead to atrophy.

Synonyms:  muscular atrophy,  DOID:767,  Amyotrophia NOS,  Amyotrophia NOS (disorder),  Muscle atrophy (disorder) ...

Linkouts:  OMIM