DISEASES

Disease-gene associations mined from literature

Human genes for peptic ulcer

Peptic ulcer [DOID:750]

A peptic ulcer, also known as PUD or peptic ulcer disease, is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is defined as mucosal erosions equal to or greater than 0.5 cm. As many as 70–90% of such ulcers are associated with Helicobacter pylori, a spiral-shaped bacterium that lives in the acidic environment of the stomach; however, only 40% of those cases go to a doctor. Ulcers can also be caused or worsened by drugs such as aspirin, ibuprofen, and other NSAIDs.

Synonyms:  peptic ulcer,  DOID:750,  acute peptic ulcer with hemorrhage,  acute peptic ulcer with hemorrhage and perforation,  acute peptic ulcer without hemorrhage AND without perforation (disorder) ...