DISEASES

Disease-gene associations mined from literature

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Human genes for subacute thyroiditis

Subacute thyroiditis [DOID:7165]

Subacute thyroiditis is a form of thyroiditis that can be a cause of both thyrotoxicosis and hypothyroidism. It is uncommon and can affect individuals of both sexes and all ages. It manifests as a sudden and painful enlargement of the thyroid gland accompanied with fever, malaise and muscle aches. Some have suggested that its cause might be viral in origin.

Synonyms:  subacute thyroiditis,  DOID:7165,  De Quervain's thyroiditis,  Giant-cell thyroiditis,  Granulomatous thyroiditis ...

The disease associations are derived via automatic text mining of the biomedical literature and have not been manually verified. The confidence of each association is signified by stars, where ★★★★☆ is the highest confidence and ★☆☆☆☆ is the lowest.

Each disease–gene association is based on a text-mining score, which is proportional to 1) the absolute number of comentionings and 2) the ratio of observed to expected comentionings (i.e. the enrichment). These scores are normalized to z-scores by comparing them to a random background. This is represented by stars, each star corresponding to two standard deviations above the mean of the background distribution.

Developed by Sune Frankild and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.