DISEASES

Disease-gene associations mined from literature

Human genes for cleft palate

Cleft palate [DOID:674]

Cleft lip (cheiloschisis) and cleft palate (palatoschisis), which can also occur together as cleft lip and palate, are variations of a type of clefting congenital deformity caused by abnormal facial development during gestation. A cleft is a fissure or opening—a gap. It is the non-fusion of the body's natural structures that form before birth. Approximately 1 in 700 children born have a cleft lip and/or a cleft palate. An older term is harelip, based on the similarity to the cleft in the lip of a hare.

Synonyms:  cleft palate,  DOID:674,  Palatoschisis,  Uranostaphyloschisis (disorder),  Uranostaphyloschisis disorder ...