Disease-gene associations mined from literature

Human genes for dentinogenesis imperfecta

Dentinogenesis imperfecta [DOID:4154]

Dentinogenesis imperfecta (hereditary Opalescent Dentin) is a genetic disorder of tooth development. This condition causes teeth to be discolored (most often a blue-gray or yellow-brown color) and translucent. Teeth are also weaker than normal, making them prone to rapid wear, breakage, and loss. These problems can affect both primary (baby) teeth and permanent teeth. This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. Dentinogenesis imperfecta affects an estimated 1 in 6,000 to 8,000 people.

Synonyms:  dentinogenesis imperfecta,  DOID:4154

Linkouts:  OMIM #1 #2