DISEASES

Disease-gene associations mined from literature

SearchDownloads

Human genes for Merkel cell carcinoma

Merkel cell carcinoma [DOID:3965]

Merkel cell carcinoma (also known as a "Cutaneous apudoma," "Primary neuroendocrine carcinoma of the skin,""Primary small cell carcinoma of the skin,"and "Trabecular carcinoma of the skin" ) is a rare and highly aggressive cancer in which malignant cancer cells develop on or just beneath the skin and in hair follicles.

Synonyms:  Merkel cell carcinoma,  DOID:3965,  Trabecular adenocarcinoma (morphologic abnormality),  trabecular carcinoma,  Trabecular adenocarcinoma morphologic abnormality ...

The disease associations are derived via automatic text mining of the biomedical literature and have not been manually verified. The confidence of each association is signified by stars, where ★★★★☆ is the highest confidence and ★☆☆☆☆ is the lowest.

Each disease–gene association is based on a text-mining score, which is proportional to 1) the absolute number of comentionings and 2) the ratio of observed to expected comentionings (i.e. the enrichment). These scores are normalized to z-scores by comparing them to a random background. This is represented by stars, each star corresponding to two standard deviations above the mean of the background distribution.

Developed by Sune Frankild and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.