DISEASES

Disease-gene associations mined from literature

Human genes for Lynch syndrome

Lynch syndrome [DOID:3883]

Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer ) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair.

Synonyms:  Lynch syndrome,  DOID:3883,  Lynch disease,  Lynch disorder,  COCA 1 ...

Linkouts:  OMIM #1 #2 #3 #4 #5 #6 #7