DISEASES

Disease-gene associations mined from literature

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Human genes for corneal dystrophy

Corneal dystrophy [DOID:2566]

Human corneal dystrophy is a group of disorders, characterised by a noninflammatory, inherited, bilateral opacity of the transparent front part of the human eye called the cornea. There are a number of rare forms varying in expression and degree of vision loss.

Synonyms:  corneal dystrophy,  DOID:2566,  Corneal dystrophy (disorder),  hereditary corneal dystrophy,  Corneal dystrophy disorder ...

The disease associations are derived via automatic text mining of the biomedical literature and have not been manually verified. The confidence of each association is signified by stars, where ★★★★☆ is the highest confidence and ★☆☆☆☆ is the lowest.

Each disease–gene association is based on a text-mining score, which is proportional to 1) the absolute number of comentionings and 2) the ratio of observed to expected comentionings (i.e. the enrichment). These scores are normalized to z-scores by comparing them to a random background. This is represented by stars, each star corresponding to two standard deviations above the mean of the background distribution.

Developed by Sune Frankild and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.