DISEASES

Disease-gene associations mined from literature

Human genes for motor neuron disease

Motor neuron disease [DOID:231]

The motor neurone diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body. They are generally progressive in nature, and can cause progressive disability and death. The drug riluzole can slow progression slightly; apart from this the medical care is supportive. The condition was first described in full by the French neurologist Jean-Martin Charcot in 1869.

Synonyms:  motor neuron disease,  DOID:231,  motor neuron disorder,  motor neuron syndrome