DISEASES

Disease-gene associations mined from literature

Human genes for Glanzmann's thrombasthenia

Glanzmann's thrombasthenia [DOID:2219]

Glanzmann's thrombasthenia is an abnormality of platelets. It is an extremely rare coagulopathy (disorder of the blood), in which the platelets lack glycoprotein IIb/IIIa (GpIIb/IIIa). As a result, no fibrinogen bridging of platelets to other platelets can occur, and the bleeding time is significantly prolonged.

Synonyms:  Glanzmann's thrombasthenia,  DOID:2219,  Glanzmanns thrombasthenia,  Glycoprotein IIb/IIIa defect,  Thrombocytasthenia ...

Linkouts:  OMIM #1 #2