DISEASES

Disease-gene associations mined from literature

Human genes for acute chest syndrome

Acute chest syndrome [DOID:1584]

A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph.

Synonyms:  acute chest syndrome,  acute chest disease,  acute chest disorder,  acute chest syndromes,  DOID:1584 ...