DISEASES

Disease-gene associations mined from literature

Human genes for primary hypertrophic osteoarthropathy

Primary hypertrophic osteoarthropathy [DOID:14283]

Pachydermoperiostosis (PDP) or Primary hypertrophic osteoathropathy (PHO) is a rare genetic disorder that affects both bones and skin. Other names are idiopathic hypertrophic osteoarthropathy or Touraine-Solente-Gole syndrome. It is mainly characterized by pachydermia (thickening of the skin), periostosis (excessive bone formation) and finger clubbing (swelling of tissue with loss of normal angle between nail and nail bed).

Synonyms:  primary hypertrophic osteoarthropathy,  DOID:14283,  Pachydermoperiostosis of nail,  Pachydermoperiostosis of nail (disorder),  Pachydermoperiostosis of nail [Ambiguous] ...