Disease-gene associations mined from literature

Human genes for childhood type dermatomyositis

Childhood type dermatomyositis [DOID:14203]

Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis. In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis. In the United States, the incidence rate of JDMS is approximately 2-3 cases per million children per year.The UK incidence is believed to be between 2-3 per million children per year, with some difference between ethnic groups. The sex ratio (Female : Male) is approximately 2:1. Other Idiopathic inflammatory myopathies include; juvenile polymyositis (PM) and juvenile inclusion-body myositis (IBM), which are extremely rare and are not as common in children as in adults.

Synonyms:  childhood type dermatomyositis,  DOID:14203,  Juvenile dermatomyositis,  childhood Dermatomyositis,  childhood type dermatomyositis (disorder) ...