DISEASES

Disease-gene associations mined from literature

Human genes for cholestasis

Cholestasis [DOID:13580]

In medicine, cholestasis is a condition where bile cannot flow from the liver to the duodenum. The two basic distinctions are an obstructive type of cholestasis where there is a mechanical blockage in the duct system such as can occur from a gallstone or malignancy and metabolic types of cholestasis which are disturbances in bile formation that can occur because of genetic defects or acquired as a side effect of many medications.

Synonyms:  cholestasis,  DOID:13580,  Cholestasis (finding),  Obstruction of bile duct,  Obstruction of bile duct (disorder) ...