DISEASES

Disease-gene associations mined from literature

Human genes for tetanus

Tetanus [DOID:11338]

A primary bacterial infectious disease that results_in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli.

Synonyms:  tetanus,  DOID:11338,  Infection due to Clostridium tetani (disorder),  Tetanus (disorder),  clostridial tetanus ...