DISEASES

Disease-gene associations mined from literature

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Human genes for paralytic squint

Paralytic squint [DOID:10863]

Strabismus (English pronunciation: /strəˈbɪzməs/; Modern Latin, from Greek στραβισμός strabismos; cf. στραβίζειν strabizein "to squint", στραβός strabos "squinting, squint-eyed"), also known as heterotropia, is a condition in which the eyes are not properly aligned with each other. It typically involves a lack of coordination between the extraocular muscles, which prevents bringing the gaze of each eye to the same point in space and preventing proper binocular vision, which may adversely affect depth perception.

Synonyms:  paralytic squint,  DOID:10863,  Incomitant dissociation,  Incomitant dissociation (disorder),  Paralytic squint NOS (disorder) ...

The disease associations are derived via automatic text mining of the biomedical literature and have not been manually verified. The confidence of each association is signified by stars, where ★★★★☆ is the highest confidence and ★☆☆☆☆ is the lowest.

Each disease–gene association is based on a text-mining score, which is proportional to 1) the absolute number of comentionings and 2) the ratio of observed to expected comentionings (i.e. the enrichment). These scores are normalized to z-scores by comparing them to a random background. This is represented by stars, each star corresponding to two standard deviations above the mean of the background distribution.

Developed by Sune Frankild and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.