DISEASES

Disease-gene associations mined from literature

JensenLab

Human genes for spinocerebellar ataxia with axonal neuropathy 2

Spinocerebellar ataxia with axonal neuropathy 2 [DOID:0050755]

An autosomal recessive cerebellar ataxia that is characterized by the onset of ataxia between age three and thirty including axonal sensorimotor neuropathy, cerebellar atrophy and elevated alpha-fetoprotein that has_material_basis_in homozygous or compound heterozygous mutation in the SETX gene on chromosome 9q34.13. Oculomotor apraxia is common, but not universal.

Synonyms:  spinocerebellar ataxia with axonal neuropathy 2,  DOID:0050755,  AOA2,  SCAN2,  SCAR1 ...