DISEASES

Disease-gene associations mined from literature

Human genes for Wolf-Hirschhorn syndrome

Wolf-Hirschhorn syndrome [DOID:0050460]

Wolf–Hirschhorn syndrome (WHS), also known as chromosome deletion 4p syndrome, Pitt-Rogers-Danks syndrome (PRDS) or Pitt syndrome, was first described in 1961 by Americans Herbert L. Cooper and Kurt Hirschhorn and, thereafter, gained worldwide attention by publications by the German Ulrich Wolf, and Hirschhorn and their co-workers, specifically their articles in the German scientific magazine Humangenetik. It is a characteristic phenotype resulting from a partial deletion of chromosomal material of the short arm of chromosome 4 (del(4p16.3)).

Synonyms:  Wolf-Hirschhorn syndrome,  DOID:0050460,  WolfHirschhorn syndrome,  Wolf-Hirschhorn disease,  Wolf-Hirschhorn disorder ...