DISEASES

Disease-gene associations mined from literature

Human genes for Stevens-Johnson syndrome

Stevens-Johnson syndrome [DOID:0050426]

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two forms of a life-threatening skin condition, in which cell death causes the epidermis to separate from the dermis. The syndrome is thought to be a hypersensitivity complex that affects the skin and the mucous membranes. Although the majority of cases are idiopathic (without a known cause), the main class of known causes is medication, followed by infections and, rarely, cancers.

Synonyms:  Stevens-Johnson syndrome,  DOID:0050426,  StevensJohnson syndrome,  Stevens-Johnson disease,  Stevens-Johnson disorder