DISEASES

Disease-gene associations mined from literature

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Human genes for Lambert-Eaton myasthenic syndrome

Lambert-Eaton myasthenic syndrome [DOID:0050214]

A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal.

Synonyms:  Lambert-Eaton myasthenic syndrome,  DOID:0050214,  LambertEaton myasthenic syndrome,  Lambert-Eaton myasthenic disease,  Lambert-Eaton myasthenic disorder ...

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.