DISEASES

Disease-gene associations mined from literature

Literature on CHST8

CHST8 [ENSP00000262622]

Carbohydrate sulfotransferase 8; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin; Belongs to the sulfotransferase 2 family.

Synonyms:  CHST8,  CHST8p,  hCHST8,  K7ENM3,  Q9H2A9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM