DISEASES

Disease-gene associations mined from literature

Literature on CHD2

CHD2 [ENSP00000377747]

Chromodomain-helicase-DNA-binding protein 2; DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity).

Synonyms:  CHD2,  CHD2p,  hCHD2,  A0A024RC75,  A0A0D9SEH6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM