DISEASES

Disease-gene associations mined from literature

Literature on COQ2

COQ2 [ENSP00000310873]

4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. ECO:0000269|PubMed:15153069, ECO:0000269|PubMed:16400613,

Synonyms:  COQ2,  COQ2p,  hCOQ2,  A0A1D8H0A6,  E2QRG7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM