DISEASES

Disease-gene associations mined from literature

Literature on GSX2

GSX2 [ENSP00000319118]

GS homeobox 2; During telencephalic development, causes ventralization of pallial progenitors and, depending on the developmental stage, specifies different neuronal fates. At early stages, necessary and sufficient to correctly specify the ventral lateral ganglionic eminence (LGE) and its major derivatives, the striatal projection neurons. At later stages, may specify LGE progenitors toward dorsal LGE fates, including olfactory bulb interneurons (By similarity). Transcription factor that binds 5'-CNAATTAG-3' DNA sequence. ; Belongs to the Antp homeobox family.

Synonyms:  GSX2,  GSX2p,  hGSX2,  D6R903,  Q9BZM3 ...

Linkouts:  STRING  Pharos  UniProt