DISEASES

Disease-gene associations mined from literature

Literature on SCARB1

SCARB1 [ENSP00000261693]

Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells . Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux . Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity . ECO:0000269|PubMed:16020694, ECO:0000269|PubMed:21226579,; Belongs to the CD36 family.

Synonyms:  SCARB1,  SCARB1p,  hSCARB1,  A0A024RBS4,  B7ZKQ9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM