DISEASES

Disease-gene associations mined from literature

Literature on SHROOM3

SHROOM3 [ENSP00000296043]

Protein Shroom3; Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers (By similarity). Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity). ; Belongs to the shroom family.

Synonyms:  SHROOM3,  SHROOM3p,  hSHROOM3,  A0A2R8Y5P9,  A0A2R8Y7T7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM