DISEASES

Disease-gene associations mined from literature

Literature on DENND4A

DENND4A [ENSP00000391167]

C-myc promoter-binding protein; Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.

Synonyms:  DENND4A,  DENND4Ap,  hDENND4A,  A0A0U1RR27,  H3BSA0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM