DISEASES

Disease-gene associations mined from literature

Literature on FOXH1

FOXH1 [ENSP00000366534]

Forkhead box protein H1; Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).

Synonyms:  FOXH1,  FOXH1p,  hFOXH1,  O75593,  O75593p ...

Linkouts:  STRING  Pharos  UniProt  OMIM