DISEASES

Disease-gene associations mined from literature

Literature on ATP5MF

ATP5MF [ENSP00000292475]

ATP synthase subunit f, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

Synonyms:  ATP5MF,  ATP5MFp,  hATP5MF,  C9JU26,  E5RKA0 ...

Linkouts:  STRING  Pharos  UniProt