DISEASES

Disease-gene associations mined from literature

Literature on GBP2

GBP2 [ENSP00000359497]

Guanylate-binding protein 2; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP . Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.

Synonyms:  GBP2,  GBP2p,  hGBP2,  P32456,  P32456p ...

Linkouts:  STRING  Pharos  UniProt  OMIM