DISEASES

Disease-gene associations mined from literature

Literature on ARHGEF12

ARHGEF12 [ENSP00000380942]

Rho guanine nucleotide exchange factor 12; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.

Synonyms:  ARHGEF12,  E9PMR6,  Q9NZN5,  E9PMR6p,  hE9PMR6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM