DISEASES

Disease-gene associations mined from literature

Literature on EIF2A

EIF2A [ENSP00000417229]

Eukaryotic translation initiation factor 2A, N-terminally processed; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner; Belongs to the WD repeat EIF2A family.

Synonyms:  EIF2A,  EIF2Ap,  hEIF2A,  C9IZE1,  F8WAE5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM