DISEASES

Disease-gene associations mined from literature

Literature on VAV2

VAV2 [ENSP00000360916]

Guanine nucleotide exchange factor VAV2; Guanine nucleotide exchange factor for the Rho family of Ras- related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).

Synonyms:  VAV2,  VAV2p,  hVAV2,  P52735,  P52735p ...

Linkouts:  STRING  Pharos  UniProt  OMIM