DISEASES

Disease-gene associations mined from literature

Literature on UPB1

UPB1 [ENSP00000324343]

Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation . Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide (PubMed:10542323, PubMed:11508704, PubMed:10415095, PubMed:29976570, PubMed:22525402, PubMed:24526388). Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). ECO:0000269|PubMed:10542323, ECO:0000269|PubMed:11508704, ECO:0000269|PubMed:22525402, ECO:0000269|PubMed:24526388, ECO:0000269|PubMed:29976570, ECO:0000305|PubMed:22525402,; Belongs to the carbon-nitrogen hydrolase superfamily. BUP family.

Synonyms:  UPB1,  UPB1p,  hUPB1,  A0A024R1H3,  F8WC94 ...

Linkouts:  STRING  Pharos  UniProt  OMIM