DISEASES

Disease-gene associations mined from literature

Literature on RNASE6

RNASE6 [ENSP00000302046]

Ribonuclease K6; Ribonuclease which shows a preference for the pyrimidines uridine and cytosine . Has potent antibacterial activity against a range of Gram-positive and Gram- negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli . Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria . Probably contributes to urinary tract sterility . Bactericidal activity is independent of RNase activity . ECO:0000269|PubMed:27013146, ECO:0000269|PubMed:27089320,

Synonyms:  RNASE6,  RNASE6p,  hRNASE6,  Q6IB39,  Q93091 ...

Linkouts:  STRING  Pharos  UniProt  OMIM