DISEASES

Disease-gene associations mined from literature

Literature on H1-2

H1-2 [ENSP00000339566]

Histone H1.2; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Synonyms:  H1-2,  HIST1H1C,  P16403,  P16403p,  hP16403 ...

Linkouts:  STRING  Pharos  UniProt  OMIM