DISEASES

Disease-gene associations mined from literature

Literature on STRA8

STRA8 [ENSP00000275764]

Stimulated by retinoic acid gene 8 protein homolog; Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (possibly in an indirect manner), and in vitro can activate DNA transcription (By similarity).

Synonyms:  STRA8,  STRA8p,  hSTRA8,  Q7Z7C7,  Q7Z7C7p ...

Linkouts:  STRING  Pharos  UniProt  OMIM