DISEASES

Disease-gene associations mined from literature

Literature on VDAC2

VDAC2 [ENSP00000361635]

Voltage-dependent anion-selective channel protein 2; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective; Belongs to the eukaryotic mitochondrial porin family.

Synonyms:  VDAC2,  VDAC2p,  hVDAC2,  A0A024QZT0,  A0A0A0MR02 ...

Linkouts:  STRING  Pharos  UniProt  OMIM