DISEASES

Disease-gene associations mined from literature

Literature on IKZF3

IKZF3 [ENSP00000344544]

Zinc finger protein Aiolos; Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. ; Belongs to the Ikaros C2H2-type zinc-finger protein family.

Synonyms:  IKZF3,  IKZF3p,  hIKZF3,  A0A0C4DGN9,  Q9UKT9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM