DISEASES

Disease-gene associations mined from literature

Literature on RXRG

RXRG [ENSP00000352900]

Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).

Synonyms:  RXRG,  A0A087WZ88,  F1D8Q7,  NR2B3,  P48443 ...

Linkouts:  STRING  Pharos  UniProt  OMIM