DISEASES

Disease-gene associations mined from literature

Literature on CPLX2

CPLX2 [ENSP00000352544]

Complexin-2; Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis (By similarity). ; Belongs to the complexin/synaphin family.

Synonyms:  CPLX2,  CPLX2p,  hCPLX2,  D6R960,  D6RBA5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM