DISEASES

Disease-gene associations mined from literature

Literature on SEH1L

SEH1L [ENSP00000382779]

Nucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore; Belongs to the WD repeat SEC13 family.

Synonyms:  SEH1L,  SEH1Lp,  hSEH1L,  K7ELV2,  K7ENI5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM