DISEASES

Disease-gene associations mined from literature

Literature on GADD45A

GADD45A [ENSP00000360025]

Growth arrest and DNA damage-inducible protein GADD45 alpha; In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase; Belongs to the GADD45 family.

Synonyms:  GADD45A,  GADD45Ap,  hGADD45A,  A0A087WZQ0,  A0A3B3ITF9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM