DISEASES

Disease-gene associations mined from literature

Literature on USP3

USP3 [ENSP00000369681]

Ubiquitin carboxyl-terminal hydrolase 3; Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.

Synonyms:  USP3,  USP3p,  hUSP3,  H0YKU8,  H0YL81 ...

Linkouts:  STRING  Pharos  UniProt  OMIM